Evaluation of clustering algorithms for protein-protein interaction networks


Sylvain Brohée and Jacques van Helden

Supplementary material


This web site contains the supplementary material for the article

Brohee, S. and van Helden, J. (2006). Evaluation of custering algorithms for protein-protein interaction networks. BMC Bioinformatics 7, 488.

A reader who reported us a mistake in one of the analyses of the second part of the article. This mistake affects the results obtained with the program MCODE on the data sets of high-throughput characterization of protein complexes (Table 6 and Figure 5). It comes from the fact that the parameters selected for MCODE in the high throughput analysis did not correspond to the optimal parameters defined in the first part of the article.

We corrected the mistake and ran the analysis of high-throughput data with the optimal parameters for MCODE. This correction increases the accuracy calculated with MCODE. The general conclusion of the article is however not changed, in the sense that
  1. The first part of the article (robustness analysis) is not affected
  2. For the analysis of high-throughput data, MCL performs better than the other algorithms, even after this correction.
A detailed errata will be sent within a few days to BMC Bioinformatics. The current site contains the corrected versions of all the tables and figures.

Click here for a corrected version of the paper.
Figures