ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

ASCL1

Function : achaete-scute family bHLH transcription factor 1
Description : This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]

Classification  

Super Class Basic domains
Class Basic helix-loop-helix factors (bHLH)
Family MyoD / ASC-related factors
Sub Family Achaete-Scute-like factors

External references

Ensembl ENSG00000139352
RefSeq NP_004307
Uniprot P50553
Aliases ASH1, HASH1, MASH1, bHLHa46
UCSC Gene coordinates chr12:102957673-102960515

External Links

JASPAR MA1100.1
Wikipedia ASCL1
WikiGenes ASCL1
Transcription Factor Encylopedia ASCL1    
GeneCards ASCL1
FactorBook ASCL1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for ASCL1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for ASCL1