ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

ATF1

Function : activating transcription factor 1
Description : This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]

Classification  

Super Class Basic domains
Class Basic leucine zipper factors (bZIP)
Family CREB-related factors
Sub Family CREB-like factors

External references

Ensembl ENSG00000123268
RefSeq NP_005162
Uniprot P18846
Aliases EWS-ATF1, FUS/ATF-1, TREB36
UCSC Gene coordinates chr12:50763681-50821161

External Links

JASPAR MA0604.1
Wikipedia ATF1
WikiGenes ATF1
Transcription Factor Encylopedia ATF1    
GeneCards ATF1
FactorBook ATF1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for ATF1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for ATF1