ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

BCL11A

Function : B-cell CLL/lymphoma 11A
Description : This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family Factors with multiple dispersed zinc fingers
Sub Family BCL11

External references

Ensembl ENSG00000119866
RefSeq NP_060484
Uniprot Q9H165
Aliases BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, DILOS, EVI9, HBFQTL5, ZNF856
UCSC Gene coordinates chr2:60451166-60553497

External Links

JASPAR BCL11A
Wikipedia BCL11A
WikiGenes BCL11A
Transcription Factor Encylopedia BCL11A    
GeneCards BCL11A
FactorBook BCL11A


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for BCL11A

MACS - Datasets excluded for BCL11A

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for BCL11A