ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

BCL6

Function : B-cell CLL/lymphoma 6
Description : The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family More than 3 adjacent zinc finger factors
Sub Family BCL6 factors

External references

Ensembl ENSG00000113916
RefSeq NP_001697
Uniprot P41182
Aliases BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
UCSC Gene coordinates chr3:187721376-187745724

External Links

JASPAR MA0463.1
Wikipedia BCL6
WikiGenes BCL6
Transcription Factor Encylopedia BCL6    
GeneCards BCL6
FactorBook BCL6


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for BCL6

MACS - Datasets excluded for BCL6

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for BCL6