ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

CEBPA

Function : CCAAT/enhancer binding protein alpha
Description : This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]

Classification  

Super Class Basic domains
Class Basic leucine zipper factors (bZIP)
Family C/EBP-related
Sub Family C/EBP

External references

Ensembl ENSG00000245848
RefSeq NP_001274353
Uniprot P49715
Aliases C/EBP-alpha, CEBP
UCSC Gene coordinates chr19:33299933-33302563

External Links

JASPAR MA0102.3
Wikipedia CEBPA
WikiGenes CEBPA
Transcription Factor Encylopedia CEBPA    
GeneCards CEBPA
FactorBook CEBPA


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for CEBPA

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for CEBPA