ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

CREB3

Function : cAMP responsive element binding protein 3
Description : This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]

Classification  

Super Class Basic domains
Class Basic leucine zipper factors (bZIP)
Family CREB-related factors
Sub Family CREB-3-like factors

External references

Ensembl ENSG00000107175
RefSeq NP_006359
Uniprot O43889
Aliases LUMAN, LZIP, sLZIP
UCSC Gene coordinates chr9:35732319-35737007

External Links

JASPAR MA0638.1
Wikipedia CREB3
WikiGenes CREB3
Transcription Factor Encylopedia CREB3
GeneCards CREB3
FactorBook CREB3


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for CREB3

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for CREB3