Function : E2F transcription factor 6
Description : This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
| Super Class | Helix-turn-helix domains |
| Class | Fork head / winged helix factors |
| Family | E2F-related factors |
| Sub Family | E2F |
| Ensembl | ENSG00000169016 |
| RefSeq | NP_997705 |
| Uniprot | O75461 |
| Aliases | E2F-6 |
| UCSC Gene coordinates | chr2:11444374-11466176 |
| JASPAR | MA0471.1 |
| Wikipedia | E2F6 |
| WikiGenes | E2F6 |
| Transcription Factor Encylopedia | E2F6 |
| GeneCards | E2F6 |
| FactorBook | E2F6 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |