Function : early growth response 1
Description : The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | C2H2 zinc finger factors |
| Family | Three-zinc finger Krüppel-related factors |
| Sub Family | EGR factors |
| Ensembl | ENSG00000120738 |
| RefSeq | NP_001955 |
| Uniprot | P18146 |
| Aliases | AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 |
| UCSC Gene coordinates | chr5:138465491-138469314 |
| JASPAR | MA0162.3 |
| Wikipedia | EGR1 |
| WikiGenes | EGR1 |
| Transcription Factor Encylopedia | EGR1 |
| GeneCards | EGR1 |
| FactorBook | EGR1 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |