ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

EOMES

Function : eomesodermin
Description : This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Classification  

Super Class Immunoglobulin fold
Class T-Box factors
Family TBrain-related factors
Sub Family None

External references

Ensembl ENSG00000163508
RefSeq NP_001265111
Uniprot O95936
Aliases TBR2
UCSC Gene coordinates chr3:27715948-27722714

External Links

JASPAR MA0800.1
Wikipedia EOMES
WikiGenes EOMES
Transcription Factor Encylopedia EOMES
GeneCards EOMES
FactorBook EOMES


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for EOMES

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for EOMES