EPAS1
Function : endothelial PAS domain protein 1
Description : This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
Classification 
| Super Class | Basic domains |
| Class | Basic helix-loop-helix factors (bHLH) |
| Family | PAS domain factors |
| Sub Family | Ahr-like factors |
External references
| Ensembl | ENSG00000116016 |
| RefSeq | NP_001421 |
| Uniprot | Q99814 |
| Aliases | ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 |
| UCSC Gene coordinates | chr2:46297401-46386702 |
External Links
| JASPAR | EPAS1 |
| Wikipedia | EPAS1 |
| WikiGenes | EPAS1 |
| Transcription Factor Encylopedia | EPAS1 |
| GeneCards | EPAS1 |
| FactorBook | EPAS1 |
