ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

ESR2

Function : estrogen receptor 2
Description : This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class Nuclear receptors with C4 zinc fingers
Family Steroid hormone receptors (NR3)
Sub Family ER-like receptors (NR3A&B)

External references

Ensembl ENSG00000140009
RefSeq NP_001278641
Uniprot Q92731
Aliases ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
UCSC Gene coordinates chr14:64226711-64338630

External Links

JASPAR MA0258.2
Wikipedia ESR2
WikiGenes ESR2
Transcription Factor Encylopedia ESR2
GeneCards ESR2
FactorBook ESR2


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for ESR2

MACS - Datasets excluded for ESR2

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for ESR2