Function : FOS like 1, AP-1 transcription factor subunit
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
| Super Class | Basic domains |
| Class | Basic leucine zipper factors (bZIP) |
| Family | Fos-related factors |
| Sub Family | Fos factors |
| Ensembl | ENSG00000175592 |
| RefSeq | NP_001287786 |
| Uniprot | P15407 |
| Aliases | FRA, FRA1, fra-1 |
| UCSC Gene coordinates | chr11:65892135-65900525 |
| JASPAR | MA0477.1 |
| Wikipedia | FOSL1 |
| WikiGenes | FOSL1 |
| Transcription Factor Encylopedia | FOSL1 |
| GeneCards | FOSL1 |
| FactorBook | FOSL1 |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |