Function : FOS like 1, AP-1 transcription factor subunit
Description : The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Super Class | Basic domains |
Class | Basic leucine zipper factors (bZIP) |
Family | Fos-related factors |
Sub Family | Fos factors |
Ensembl | ENSG00000175592 |
RefSeq | NP_001287786 |
Uniprot | P15407 |
Aliases | FRA, FRA1, fra-1 |
UCSC Gene coordinates | chr11:65892135-65900525 |
JASPAR | MA0477.1 |
Wikipedia | FOSL1 |
WikiGenes | FOSL1 |
Transcription Factor Encylopedia | FOSL1 |
GeneCards | FOSL1 |
FactorBook | FOSL1 |
Datasets quality |
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DNA constraint | Motifs | ![]() |
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UCSC genome browser |
All peaks | BED file | ![]() |
Merged peaks (non-redundant peaks) |
BED file | ![]() |
Peak sequences | FASTA file |
Datasets quality |
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DNA constraint | Motifs | ![]() |
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UCSC genome browser |
All peaks | BED file | ![]() |
Merged peaks (non-redundant peaks) |
BED file | ![]() |
Peak sequences | FASTA file |