ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

HDAC3

Function : histone deacetylase 3
Description : Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

Classification  

Super Class Unknown
Class Unknown
Family Unknown
Sub Family Unknown

External references

Ensembl ENSG00000171720
RefSeq NP_003874
Uniprot O15379
Aliases HD3, RPD3, RPD3-2
UCSC Gene coordinates chr5:141620875-141636859

External Links

JASPAR HDAC3
Wikipedia HDAC3
WikiGenes HDAC3
Transcription Factor Encylopedia HDAC3    
GeneCards HDAC3
FactorBook HDAC3


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for HDAC3

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for HDAC3