ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

HNF1B

Function : HNF1 homeobox B
Description : This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Classification  

Super Class Helix-turn-helix domains
Class Homeo domain factors
Family POU domain factors
Sub Family HNF1-like factors

External references

Ensembl ENSG00000276194
RefSeq NP_001159395
Uniprot P35680
Aliases FJHN, HNF-1-beta, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1
UCSC Gene coordinates chr17:37686430-37745077

External Links

JASPAR MA0153.2
Wikipedia HNF1B
WikiGenes HNF1B
Transcription Factor Encylopedia HNF1B
GeneCards HNF1B
FactorBook HNF1B


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for HNF1B

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for HNF1B