ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

HNF4A

Function : hepatocyte nuclear factor 4 alpha
Description : The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class Nuclear receptors with C4 zinc fingers
Family RXR-related receptors (NR2)
Sub Family HNF-4 (NR2A)

External references

Ensembl ENSG00000101076
RefSeq NP_001274113
Uniprot P41235
Aliases FRTS4, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14
UCSC Gene coordinates chr20:44355800-44432844

External Links

JASPAR MA0114.3
Wikipedia HNF4A
WikiGenes HNF4A
Transcription Factor Encylopedia HNF4A
GeneCards HNF4A
FactorBook HNF4A


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for HNF4A

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for HNF4A