Function : interferon regulatory factor 2
Description : IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4. [provided by RefSeq, Jul 2008]
| Super Class | Helix-turn-helix domains |
| Class | Tryptophan cluster factors |
| Family | Interferon-regulatory factors |
| Sub Family | None |
| Ensembl | ENSG00000168310 |
| RefSeq | NP_002190 |
| Uniprot | P14316 |
| Aliases | IRF-2 |
| UCSC Gene coordinates | chr4:184387721-184474571 |
| JASPAR | MA0051.1 |
| Wikipedia | IRF2 |
| WikiGenes | IRF2 |
| Transcription Factor Encylopedia | IRF2 |
| GeneCards | IRF2 |
| FactorBook | IRF2 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |