ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

IRF3

Function : interferon regulatory factor 3
Description : This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Classification  

Super Class Helix-turn-helix domains
Class Tryptophan cluster factors
Family Interferon-regulatory factors
Sub Family None

External references

Ensembl ENSG00000126456
RefSeq NP_001184051
Uniprot Q14653
Aliases IIAE7
UCSC Gene coordinates chr19:49659568-49665874

External Links

JASPAR MA1418.1
Wikipedia IRF3
WikiGenes IRF3
Transcription Factor Encylopedia IRF3    
GeneCards IRF3
FactorBook IRF3


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for IRF3

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for IRF3