KLF1
Function : Kruppel like factor 1
Description : This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]
Classification 
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | C2H2 zinc finger factors |
| Family | Three-zinc finger Krüppel-related factors |
| Sub Family | Krüppel-like factors |
External references
| Ensembl | ENSG00000105610 |
| RefSeq | NP_006554 |
| Uniprot | Q13351 |
| Aliases | EKLF |
| UCSC Gene coordinates | chr19:12884421-12887202 |
External Links
| JASPAR | MA0493.1 |
| Wikipedia | KLF1 |
| WikiGenes | KLF1 |
| Transcription Factor Encylopedia | KLF1 |
| GeneCards | KLF1 |
| FactorBook | KLF1 |
