ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

KLF4

Function : Kruppel like factor 4
Description : This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family Three-zinc finger Krüppel-related factors
Sub Family Krüppel-like factors

External references

Ensembl ENSG00000136826
RefSeq NP_001300981
Uniprot O43474
Aliases EZF, GKLF
UCSC Gene coordinates chr9:107484851-107489719

External Links

JASPAR MA0039.3
Wikipedia KLF4
WikiGenes KLF4
Transcription Factor Encylopedia KLF4    
GeneCards KLF4
FactorBook KLF4


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for KLF4

MACS - Datasets excluded for KLF4

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for KLF4