Function : Kruppel like factor 5
Description : This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | C2H2 zinc finger factors |
| Family | Three-zinc finger Krüppel-related factors |
| Sub Family | Krüppel-like factors |
| Ensembl | ENSG00000102554 |
| RefSeq | NP_001721 |
| Uniprot | Q13887 |
| Aliases | BTEB2, CKLF, IKLF |
| UCSC Gene coordinates | chr13:73054975-73077541 |
| JASPAR | MA0599.1 |
| Wikipedia | KLF5 |
| WikiGenes | KLF5 |
| Transcription Factor Encylopedia | KLF5 |
| GeneCards | KLF5 |
| FactorBook | KLF5 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |