ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

MAX

Function : MYC associated factor X
Description : The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Classification  

Super Class Basic domains
Class Basic helix-loop-helix factors (bHLH)
Family bHLH-ZIP factors
Sub Family Myc / Max factors

External references

Ensembl ENSG00000125952
RefSeq NP_001257998
Uniprot P61244
Aliases bHLHd4
UCSC Gene coordinates chr14:65006100-65102694

External Links

JASPAR MA0058.3
Wikipedia MAX
WikiGenes MAX
Transcription Factor Encylopedia MAX    
GeneCards MAX
FactorBook MAX


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for MAX

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for MAX