ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

MNT

Function : MAX network transcriptional repressor
Description : The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]

Classification  

Super Class Basic domains
Class Basic helix-loop-helix factors (bHLH)
Family bHLH-ZIP factors
Sub Family Mad-like factors

External references

Ensembl ENSG00000070444
RefSeq NP_064706
Uniprot Q99583
Aliases MAD6, MXD6, ROX, bHLHd3
UCSC Gene coordinates chr17:2384059-2400963

External Links

JASPAR MA0825.1
Wikipedia MNT
WikiGenes MNT
Transcription Factor Encylopedia MNT    
GeneCards MNT
FactorBook MNT


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for MNT

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for MNT