Function : MYB proto-oncogene like 2
Description : The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
| Super Class | Helix-turn-helix domains |
| Class | Tryptophan cluster factors |
| Family | Myb/SANT domain factors |
| Sub Family | Myb-like factors |
| Ensembl | ENSG00000101057 |
| RefSeq | NP_002457 |
| Uniprot | P10244 |
| Aliases | B-MYB, BMYB |
| UCSC Gene coordinates | chr20:43667018-43716495 |
| JASPAR | MA0777.1 |
| Wikipedia | MYBL2 |
| WikiGenes | MYBL2 |
| Transcription Factor Encylopedia | MYBL2 |
| GeneCards | MYBL2 |
| FactorBook | MYBL2 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |