ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

NCOR2

Function : nuclear receptor corepressor 2
Description : This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011]

Classification  

Super Class Helix-turn-helix domains
Class Tryptophan cluster factors
Family Myb/SANT domain factors
Sub Family NCoR-like factors

External references

Ensembl ENSG00000196498
RefSeq NP_006303
Uniprot Q9Y618
Aliases CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
UCSC Gene coordinates chr12:124324410-124567463

External Links

JASPAR NCOR2
Wikipedia NCOR2
WikiGenes NCOR2
Transcription Factor Encylopedia NCOR2    
GeneCards NCOR2
FactorBook NCOR2


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for NCOR2

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for NCOR2