ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

NFATC1

Function : nuclear factor of activated T-cells 1
Description : The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq, Jul 2013]

Classification  

Super Class Immunoglobulin fold
Class Rel homology region (RHR) factors
Family NFAT-related factors
Sub Family None

External references

Ensembl ENSG00000131196
RefSeq NP_006153
Uniprot O95644
Aliases NF-ATC, NF-ATc1.2, NFAT2, NFATc
UCSC Gene coordinates chr18:79395771-79529322

External Links

JASPAR MA0624.1
Wikipedia NFATC1
WikiGenes NFATC1
Transcription Factor Encylopedia NFATC1    
GeneCards NFATC1
FactorBook NFATC1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for NFATC1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for NFATC1