ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

NFKB2

Function : nuclear factor kappa B subunit 2
Description : This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Classification  

Super Class Immunoglobulin fold
Class Rel homology region (RHR) factors
Family NF-kappaB-related factors
Sub Family NF-kappaB p50 subunit-like factors

External references

Ensembl ENSG00000077150
RefSeq NP_001309864
Uniprot Q00653
Aliases CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52
UCSC Gene coordinates chr10:102394109-102402528

External Links

JASPAR MA0778.1
Wikipedia NFKB2
WikiGenes NFKB2
Transcription Factor Encylopedia NFKB2
GeneCards NFKB2
FactorBook NFKB2


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for NFKB2

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for NFKB2