ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

NFKBIA

Function : NFKB inhibitor alpha
Description : This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]

Classification  

Super Class Immunoglobulin fold
Class Rel homology region (RHR) factors
Family Ankyrin domain-only factors
Sub Family IkappaB-related factors

External references

Ensembl ENSG00000100906
RefSeq NP_065390
Uniprot P25963
Aliases IKBA, MAD-3, NFKBI
UCSC Gene coordinates chr14:35401509-35404753

External Links

JASPAR NFKBIA
Wikipedia NFKBIA
WikiGenes NFKBIA
Transcription Factor Encylopedia NFKBIA    
GeneCards NFKBIA
FactorBook NFKBIA


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for NFKBIA

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for NFKBIA