ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

NFYA

Function : nuclear transcription factor Y subunit alpha
Description : The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. [provided by RefSeq, Jul 2008]

Classification  

Super Class Other all-alpha-helical DNA-binding domains
Class Heteromeric CCAAT-binding factors
Family Heteromeric CCAAT-binding factors
Sub Family None

External references

Ensembl ENSG00000001167
RefSeq NP_002496
Uniprot P23511
Aliases CBF-A, CBF-B, HAP2, NF-YA
UCSC Gene coordinates chr6:41072967-41102406

External Links

JASPAR MA0060.1
Wikipedia NFYA
WikiGenes NFYA
Transcription Factor Encylopedia NFYA    
GeneCards NFYA
FactorBook NFYA


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for NFYA

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for NFYA