Function : nuclear transcription factor Y subunit beta
Description : The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]
| Super Class | Other all-alpha-helical DNA-binding domains |
| Class | Heteromeric CCAAT-binding factors |
| Family | Heteromeric CCAAT-binding factors |
| Sub Family | None |
| Ensembl | ENSG00000120837 |
| RefSeq | NP_006157 |
| Uniprot | P25208 |
| Aliases | CBF-A, CBF-B, HAP3, NF-YB |
| UCSC Gene coordinates | chr12:104117079-104138261 |
| JASPAR | MA0502.1 |
| Wikipedia | NFYB |
| WikiGenes | NFYB |
| Transcription Factor Encylopedia | NFYB |
| GeneCards | NFYB |
| FactorBook | NFYB |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |