ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

NR2C2

Function : nuclear receptor subfamily 2 group C member 2
Description : This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class Nuclear receptors with C4 zinc fingers
Family RXR-related receptors (NR2)
Sub Family Testicular receptors (NR2C)

External references

Ensembl ENSG00000177463
RefSeq NP_001278623
Uniprot P49116
Aliases TAK1, TR4
UCSC Gene coordinates chr3:14947583-15049278

External Links

JASPAR MA0504.1
Wikipedia NR2C2
WikiGenes NR2C2
Transcription Factor Encylopedia NR2C2
GeneCards NR2C2
FactorBook NR2C2


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for NR2C2

MACS - Datasets excluded for NR2C2

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for NR2C2