Function : nuclear receptor subfamily 4 group A member 1
Description : This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | Nuclear receptors with C4 zinc fingers |
| Family | NGFI-B-related receptors (NR4) |
| Sub Family | None |
| Ensembl | ENSG00000123358 |
| RefSeq | NP_001189163 |
| Uniprot | P22736 |
| Aliases | GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3 |
| UCSC Gene coordinates | chr12:52022831-52059506 |
| JASPAR | MA1112.1 |
| Wikipedia | NR4A1 |
| WikiGenes | NR4A1 |
| Transcription Factor Encylopedia | NR4A1 |
| GeneCards | NR4A1 |
| FactorBook | NR4A1 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |