ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

OVOL2

Function : ovo like zinc finger 2
Description : This gene encodes a member of the evolutionarily conserved ovo-like protein family. Mammalian members of this family contain a single zinc finger domain composed of a tetrad of C2H2 zinc fingers with variable N- and C-terminal extensions that contain intrinsically disordered domains. Members of this family are involved in epithelial development and differentiation. Knockout of this gene in mouse results in early embryonic lethality with phenotypes that include neurectoderm expansion, impaired vascularization, and heart anomalies. In humans, allelic variants of this gene have been associated with posterior polymorphous corneal dystrophy. [provided by RefSeq, Apr 2016]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family More than 3 adjacent zinc finger factors
Sub Family OVOL-factors

External references

Ensembl ENSG00000125850
RefSeq NP_067043
Uniprot Q9BRP0
Aliases CHED, CHED1, CHED2, EUROIMAGE566589, PPCD1, ZNF339
UCSC Gene coordinates chr20:18024151-18059187

External Links

JASPAR OVOL2
Wikipedia OVOL2
WikiGenes OVOL2
Transcription Factor Encylopedia OVOL2    
GeneCards OVOL2
FactorBook OVOL2


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for OVOL2

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for OVOL2