ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

PAX6

Function : paired box 6
Description : This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]

Classification  

Super Class Helix-turn-helix domains
Class Paired box factors
Family Paired plus homeo domain
Sub Family PAX-4/6

External references

Ensembl ENSG00000007372
RefSeq NP_000271
Uniprot P26367
Aliases AN, AN2, ASGD5, D11S812E, FVH1, MGDA, WAGR
UCSC Gene coordinates chr11:31784791-31817960

External Links

JASPAR MA0069.1
Wikipedia PAX6
WikiGenes PAX6
Transcription Factor Encylopedia PAX6
GeneCards PAX6
FactorBook PAX6


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for PAX6

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for PAX6