ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

PAX8

Function : paired box 8
Description : This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

Classification  

Super Class Helix-turn-helix domains
Class Paired box factors
Family Paired domain only
Sub Family PAX-2-like factors (partial homeobox)

External references

Ensembl ENSG00000125618
RefSeq NP_039247
Uniprot Q06710
Aliases -
UCSC Gene coordinates chr2:113215996-113278949

External Links

JASPAR PAX8
Wikipedia PAX8
WikiGenes PAX8
Transcription Factor Encylopedia PAX8
GeneCards PAX8
FactorBook PAX8


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for PAX8

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for PAX8