ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

PDX1

Function : pancreatic and duodenal homeobox 1
Description : The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (IDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Aug 2017]

Classification  

Super Class Helix-turn-helix domains
Class Homeo domain factors
Family HOX-related factors
Sub Family PDX

External references

Ensembl ENSG00000139515
RefSeq NP_000200
Uniprot P52945
Aliases GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
UCSC Gene coordinates chr13:27919981-27926313

External Links

JASPAR MA0132.2
Wikipedia PDX1
WikiGenes PDX1
Transcription Factor Encylopedia PDX1    
GeneCards PDX1
FactorBook PDX1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for PDX1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for PDX1