ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

PPARG

Function : peroxisome proliferator activated receptor gamma
Description : This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class Nuclear receptors with C4 zinc fingers
Family Thyroid hormone receptor-related factors (NR1)
Sub Family PPAR (NR1C)

External references

Ensembl ENSG00000132170
RefSeq NP_619726
Uniprot P37231
Aliases CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma
UCSC Gene coordinates chr3:12287849-12471053

External Links

JASPAR MA0066.1
Wikipedia PPARG
WikiGenes PPARG
Transcription Factor Encylopedia PPARG
GeneCards PPARG
FactorBook PPARG


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for PPARG

MACS - Datasets excluded for PPARG

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for PPARG