Function : prospero homeobox 1
Description : The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
| Super Class | Helix-turn-helix domains |
| Class | Homeo domain factors |
| Family | HD-PROS factors |
| Sub Family | None |
| Ensembl | ENSG00000117707 |
| RefSeq | NP_001257545 |
| Uniprot | Q92786 |
| Aliases | - |
| UCSC Gene coordinates | chr1:213983238-214041509 |
| JASPAR | MA0794.1 |
| Wikipedia | PROX1 |
| WikiGenes | PROX1 |
| Transcription Factor Encylopedia | PROX1 |
| GeneCards | PROX1 |
| FactorBook | PROX1 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |