Function : retinoic acid receptor alpha
Description : This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | Nuclear receptors with C4 zinc fingers |
| Family | Thyroid hormone receptor-related factors (NR1) |
| Sub Family | Retinoic acid receptors (NR1B) |
| Ensembl | ENSG00000131759 |
| RefSeq | NP_000955 |
| Uniprot | P10276 |
| Aliases | NR1B1, RAR |
| UCSC Gene coordinates | chr17:40309170-40357642 |
| JASPAR | MA0159.1 MA0730.1 |
| Wikipedia | RARA |
| WikiGenes | RARA |
| Transcription Factor Encylopedia | RARA |
| GeneCards | RARA |
| FactorBook | RARA |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |