ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

RB1

Function : RB transcriptional corepressor 1
Description : The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Classification  

Super Class Unknown
Class Unknown
Family Unknown
Sub Family Unknown

External references

Ensembl ENSG00000139687
RefSeq NP_000312
Uniprot P06400
Aliases OSRC, PPP1R130, RB, p105-Rb, pRb, pp110
UCSC Gene coordinates chr13:48303746-48481889

External Links

JASPAR RB1
Wikipedia RB1
WikiGenes RB1
Transcription Factor Encylopedia RB1    
GeneCards RB1
FactorBook RB1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for RB1

MACS - Datasets excluded for RB1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for RB1