ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

RELA

Function : RELA proto-oncogene, NF-kB subunit
Description : NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Classification  

Super Class Immunoglobulin fold
Class Rel homology region (RHR) factors
Family NF-kappaB-related factors
Sub Family NF-kappaB p65 subunit-like factors

External references

Ensembl ENSG00000173039
RefSeq NP_001230913
Uniprot Q04206
Aliases NFKB3, p65
UCSC Gene coordinates chr11:65653595-65662971

External Links

JASPAR MA0107.1
Wikipedia RELA
WikiGenes RELA
Transcription Factor Encylopedia RELA    
GeneCards RELA
FactorBook RELA


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for RELA

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for RELA