ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

RFX1

Function : regulatory factor X1
Description : This gene encodes a member of the regulatory factor X (RFX) family of transcription factors, which are characterized by a winged-helix DNA-binding domain. The encoded transcription factor contains an N-terminal activation domain and a C-terminal repression domain, and may activate or repress target gene expression depending on cellular context. This transcription factor has been shown to regulate a wide variety of genes involved in immunity and cancer, including the MHC class II genes and genes that may be involved in cancer progression. This gene exhibits altered expression in glioblastoma and the autoimmune disease systemic lupus erythematosis (SLE). [provided by RefSeq, Jul 2016]

Classification  

Super Class Helix-turn-helix domains
Class Fork head / winged helix factors
Family RFX-related factors
Sub Family None

External references

Ensembl ENSG00000132005
RefSeq NP_002909
Uniprot P22670
Aliases EFC, RFX
UCSC Gene coordinates chr19:13961529-14007513

External Links

JASPAR MA0509.1
Wikipedia RFX1
WikiGenes RFX1
Transcription Factor Encylopedia RFX1    
GeneCards RFX1
FactorBook RFX1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for RFX1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for RFX1