Function : regulatory factor X2
Description : This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
| Super Class | Helix-turn-helix domains |
| Class | Fork head / winged helix factors |
| Family | RFX-related factors |
| Sub Family | None |
| Ensembl | ENSG00000087903 |
| RefSeq | NP_000626 |
| Uniprot | P48378 |
| Aliases | - |
| UCSC Gene coordinates | chr19:5993163-6110652 |
| JASPAR | MA0600.2 |
| Wikipedia | RFX2 |
| WikiGenes | RFX2 |
| Transcription Factor Encylopedia | RFX2 |
| GeneCards | RFX2 |
| FactorBook | RFX2 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |