ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

RUNX1T1

Function : RUNX1 translocation partner 1
Description : This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Classification  

Super Class Unknown
Class Unknown
Family Unknown
Sub Family Unknown

External references

Ensembl ENSG00000079102
RefSeq NP_783552
Uniprot Q06455
Aliases AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
UCSC Gene coordinates chr8:91954966-92103364

External Links

JASPAR RUNX1T1
Wikipedia RUNX1T1
WikiGenes RUNX1T1
Transcription Factor Encylopedia RUNX1T1    
GeneCards RUNX1T1
FactorBook RUNX1T1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for RUNX1T1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for RUNX1T1