ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

RUNX3

Function : runt related transcription factor 3
Description : This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Classification  

Super Class Immunoglobulin fold
Class Runt domain factors
Family Runt-related factors
Sub Family None

External references

Ensembl ENSG00000020633
RefSeq NP_004341
Uniprot Q13761
Aliases AML2, CBFA3, PEBP2aC
UCSC Gene coordinates chr1:24899510-24965157

External Links

JASPAR MA0684.1
Wikipedia RUNX3
WikiGenes RUNX3
Transcription Factor Encylopedia RUNX3    
GeneCards RUNX3
FactorBook RUNX3


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for RUNX3

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for RUNX3