ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SIRT6

Function : sirtuin 6
Description : This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

Classification  

Super Class Unknown
Class Unknown
Family Unknown
Sub Family Unknown

External references

Ensembl ENSG00000077463
RefSeq NP_001307992
Uniprot Q8N6T7
Aliases SIR2L6
UCSC Gene coordinates chr19:4174108-4182603

External Links

JASPAR SIRT6
Wikipedia SIRT6
WikiGenes SIRT6
Transcription Factor Encylopedia SIRT6    
GeneCards SIRT6
FactorBook SIRT6


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for SIRT6

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for SIRT6