ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SMAD3

Function : SMAD family member 3
Description : The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

Classification  

Super Class beta-Hairpin exposed by an alpha/beta-scaffold
Class SMAD/NF-1 DNA-binding domain factors
Family SMAD factors
Sub Family Regulatory Smads (R-Smad)

External references

Ensembl ENSG00000166949
RefSeq NP_005893
Uniprot P84022
Aliases HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3
UCSC Gene coordinates chr15:67065697-67195194

External Links

JASPAR MA0795.1
Wikipedia SMAD3
WikiGenes SMAD3
Transcription Factor Encylopedia SMAD3    
GeneCards SMAD3
FactorBook SMAD3


Genomic visualization & Analyses for MACS

Datasets
quality 		DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)		 BED file
Peak sequences FASTA file

MACS - Datasets retained for SMAD3

MACS - Datasets excluded for SMAD3

Genomic visualization & Analyses for JAMM

Datasets
quality 		DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)		 BED file
Peak sequences FASTA file

JAMM - Datasets retained for SMAD3