SMAD5
Function : SMAD family member 5
Description : The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Classification 
| Super Class | beta-Hairpin exposed by an alpha/beta-scaffold |
| Class | SMAD/NF-1 DNA-binding domain factors |
| Family | SMAD factors |
| Sub Family | Regulatory Smads (R-Smad) |
External references
| Ensembl | ENSG00000113658 |
| RefSeq | NP_001001419 |
| Uniprot | Q99717 |
| Aliases | DWFC, JV5-1, MADH5 |
| UCSC Gene coordinates | chr5:136132844-136182733 |
External Links
| JASPAR | SMAD5 |
| Wikipedia | SMAD5 |
| WikiGenes | SMAD5 |
| Transcription Factor Encylopedia | SMAD5 |
| GeneCards | SMAD5 |
| FactorBook | SMAD5 |
