Function : snail family transcriptional repressor 2
Description : This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | C2H2 zinc finger factors |
| Family | More than 3 adjacent zinc finger factors |
| Sub Family | Snail-like factors |
| Ensembl | ENSG00000019549 |
| RefSeq | NP_003059 |
| Uniprot | O43623 |
| Aliases | SLUG, SLUGH, SLUGH1, SNAIL2, WS2D |
| UCSC Gene coordinates | chr8:48917676-48921439 |
| JASPAR | MA0745.1 |
| Wikipedia | SNAI2 |
| WikiGenes | SNAI2 |
| Transcription Factor Encylopedia | SNAI2 |
| GeneCards | SNAI2 |
| FactorBook | SNAI2 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |