ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SOX2

Function : SRY-box 2
Description : This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]

Classification  

Super Class Other all-alpha-helical DNA-binding domains
Class High-mobility group (HMG) domain factors
Family SOX-related factors
Sub Family Group B

External references

Ensembl ENSG00000181449
RefSeq NP_003097
Uniprot P48431
Aliases ANOP3, MCOPS3
UCSC Gene coordinates chr3:181711923-181714435

External Links

JASPAR MA0143.3
Wikipedia SOX2
WikiGenes SOX2
Transcription Factor Encylopedia SOX2    
GeneCards SOX2
FactorBook SOX2


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for SOX2

MACS - Datasets excluded for SOX2

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for SOX2